MCN post-doc Danai Riga and PIs Sabine Spijker and Guus Smit present first evidence for a molecular mechanism for the cognitive deficits in depression using a rat model in the 20 December issue of Science Translational Medicine.
The CNCR ‘Shisa’ team presents the characterization of a yet unknown glutamate receptor auxiliary subunit important for learning and memory. Their findings are currently available in the open access journal eLife.
A main challenge in genome-wide association studies (GWAS) is to interpret statistical findings in biological context. Post-GWAS annotation facilitates this task yet currently available tools can be time consuming and do not provide integrated visual aids for data interpretation. PhD student Kyoko Watanabe from the Department Complex Trait Genetics developed FUMA: an integrative web-based platform using information from multiple biological resources to facilitate functional annotation of GWAS results, gene prioritization and interactive visualization. The accompanying paper was published this week in Nature Communications.
At the annual meeting of the graduate school Neurosciences Amsterdam and Rotterdam (ONWAR) CNCR members Marieke van Ziel, Vincent Huson, Marinka Brouwer, Claudia Persoon and Mariana Raimundo Pinto de Matos won the Blitz presentation and oral presentation prices.