The Neurospector team has joined a European collaborative project, subsidized by the dutch research council (ZonMw), focused on accelerating therapeutic development for rare neurodevelopmental disorders through drug repurposing strategies.
Seven partners from 6 countries including FGA and ESCO will develop new strategies using cellular assays based on IPSC-derived patient neurons and biomarker analyses.
A recent study from the Molecular Neurodegeneration lab led by Wiep Scheper (FGA) has been published in Science Advances. In this work first author Jasper Smits and colleagues from FGA and MCN elucidated a previously unknown intrinsic resilience mechanism against tau aggregation in neurons.
The CNCR focuses on the mechanistic understanding of gene function in the context of cognitive function.
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