Functional Genomics

Functional Genomics

VU University & Amsterdam UMC
Human Genetics Department

Center for Neurogenomics and Cognitive Research
Amsterdam Neuroscience


The Functional Genomics department studies the presynaptic nerve terminal in health and disease.
We study presynaptic mechanisms that adjust synaptic transmission (presynaptic plasticity), the trafficking & fusion of neuropeptide vesicles (dense core vesicles) and presynaptic mechanisms of degeneration.

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Outreach & Dissemination

We love to share our work & insights with society. We have produced short films on brain myths and the Virtual Brain Experience, that allows you to see the brain from within. We also collaborate with the Museumnacht and explain our science to lay people, school children, patients & their caretakers and clinicians.

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About us

The Functional Genomics (FGA) department was established in 2001 when Matthijs Verhage moved in from Utrecht with a small team.

FGA is part of the Human Genetics Department of Amsterdam UMC, as well as the Life Sciences faculty of the VU University. Furthermore, FGA is embedded in Amsterdam Neuroscience.

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Our latest activities

Tauopathy Challenge Workshop Grant for Rik van der Kant

Dr. van der Kant, group leader of the Dementia Discovery Group at the CNCR, has received a $500.000 award to study how lipids contribute to primary Tauopathies such as progressive supranuclear palsy (PSP) and frontotemporal dementia (FTD).

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