The Hersenstichting has awarded prof. dr. Wiep Scheper of the Molecular Neurodegeneration lab at FGA with €500.000 to follow up their research on Granulovacuolar degeneration bodies (GVBs). GVBs are found in a subset of neurons with early tau pathology in the brain of persons with Alzheimer’s disease and tau-related frontomporal dementias.
Max Koppers (FGA) was awarded a VIDI grant from NWO for his project ‘Local regulation of brain connectivity’ to investigate the role of mRNA localization and local protein production in synapse formation.
Altered lipid metabolism in the brain is a key feature of many neurodegenerative diseases, yet comparing lipid data across studies has remained a challenge. To address this, Femke Feringa and Sascha Koppes-den Hertog from the dementia discovery team of Rik van der Kant (FGA-CNCR) together with the lipidomics and metabolomics team of Martin Giera at the LUMC in Leiden have developed the Neurolipid Atlas (available at neurolipidatlas.com).
The CNCR focuses on the mechanistic understanding of gene function in the context of cognitive function.
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