Dr. Rik van der Kant (CNCR-FGA) and colleagues report that accumulation of cholesterol in Alzheimer’s disease neurons drives early Tau- and Amyloid pathology, and can be reversed by cholesterol-targeting drugs. Published in Cell Stem Cell.
Claudia Persoon (CNCR-FGA) & the DCV team published a study on how many secretory vesicles are found in different CNS neurons (this paper is about vesicle pools, not swimming pools!) and how many vesicles fuse upon stimulation. The paper is featured on the cover of EMBO J. this month.
On Oct. 13, the 1st STXBP1 Patient Clinic Day will take place at VUmc in Amsterdam. The day is part of our studies on STXBP1-Encephalopathy (STXBP1-E) in a collaboration between FGA-CNCR, Clinical Genetics and VU spin-off company NBT Analytics.