Amélie Freal (FGA) was awarded a Vidi grant from NWO for her project “Neurons in balance” to investigate the mechanisms controlling axon initial segment plasticity and how this regulates network activity homeostasis.
The grant of 850 000 euro will allow her to expand her research team to further investigate how changes in neuronal activity differentially affects AIS composition in excitatory and inhibitory neurons, and how this differential plasticity participates in network homeostasis during sensory-dependent experience.
This project will use proteomics and transcriptomics approaches in cultured neurons and in vivo, coupled to super-resolution imaging and electrophysiology.
There will be PhD and post-doc positions opening in the AIS lab (see lab website: https://cncr.nl/research-team/axon_initial_segment_biology/)
More information on awarded Vidi projects can be found here.