A study by Enqi He (CNCR-FGA) published in Nature Communications demonstrates how synaptic vesicles remain in a high-energy (‘primed’) state, ready to be released. Two proteins, Munc13-1 and Munc18-1, stabilize the primed state by preventing de-priming and hereby support high frequency synaptic transmission.
An international team of researchers, including Danielle Posthuma of the VU & VUMC Amsterdam, identified Rare Copy Number Variants in NRXN1 and CNTN6 that increase the risk for Tourette Syndrome. The findings were published in Neuron, June 21.
An international team of researchers has found, for the first time, seven risk genes for insomnia. With this finding the researchers have taken an important step towards the unravelling of the biological mechanisms that cause insomnia. In addition, the finding proves that insomnia is not, as is often claimed, a purely psychological condition. Today, Nature Genetics publishes the results of this research.