FLAMES

FLAMES is a machine-learning tool that predicts genes from GWAS discovery studies. The primary publication linked to this tool:

Schipper M, de Leeuw CA, Maciel BAPC, Wightman DP, Hubers N, Boomsma DI, O’Donovan MC, Posthuma D. Prioritizing effector genes at trait-associated loci using multimodal evidence. Nat Genet. 2025 Feb;57(2):323-333. doi: 10.1038/s41588-025-02084-7. Epub 2025 Feb 10. PMID: 39930082. https://www.nature.com/articles/s41588-025-02084-7. 

Please refer to this reference when using FLAMES in a publication.

Software can be downloaded here:
https://github.com/Marijn-Schipper/FLAMES