2015

• Gao P, Limpens JH, Spijker S, Vanderschuren LJ, Voorn P. Stable immediate
early gene expression patterns in medial prefrontal cortex and striatum after
long-term cocaine self-administration. Addict Biol. 2015 Nov 24. doi:
10.1111/adb.12330. [Epub ahead of print]
PubMed PMID: 26598422.

• Schreiber J, Végh MJ, Dawitz J, Kroon T, Loos M, Labonté D, Li KW, Van Nierop
P, Van Diepen MT, De Zeeuw CI, Kneussel M, Meredith RM, Smit AB, Van Kesteren RE. Ubiquitin ligase TRIM3 controls hippocampal plasticity and learning by regulating synaptic γ-actin levels. J Cell Biol. 2015 Nov 9;211(3):569-86. doi:
10.1083/jcb.201506048.
PubMed PMID: 26527743; PubMed Central PMCID: PMC4639863.

• Riga D, Theijs JT, De Vries TJ, Smit AB, Spijker S. Social defeat-induced
anhedonia: effects on operant sucrose-seeking behavior. Front Behav Neurosci.
2015 Aug 7;9:195. doi: 10.3389/fnbeh.2015.00195.
PubMed PMID: 26300748; PubMed Central PMCID: PMC4528167.

• Loos M, Koopmans B, Aarts E, Maroteaux G, van der Sluis S; Neuro-BSIK Mouse
Phenomics Consortium., Verhage M, Smit AB. Within-strain variation in behavior
differs consistently between common inbred strains of mice. Mamm Genome 2015 Aug;26(7-8):348-54. doi: 10.1007/s00335-015-9578-7.
PubMed PMID: 26123533.

• Otvos RA, Iyer JK, van Elk R, Ulens C, Niessen WM, Somsen GW, Kini RM, Smit
AB, Kool J. Development of Plate Reader and On-Line Microfluidic Screening to
Identify Ligands of the 5-Hydroxytryptamine Binding Protein in Venoms. *Toxins
(Basel)* 2015 Jun 24;7(7):2336-53. doi: 10.3390/toxins7072336. PubMed PMID:
26114334; PubMed Central PMCID: PMC4516916.

• Fernández E, Li KW, Rajan N, De Rubeis S, Fiers M, Smit AB, Achsel T, Bagni
C. FXR2P Exerts a Positive Translational Control and Is Required for the
Activity-Dependent Increase of PSD95 Expression. J Neurosci. 2015 Jun
24;35(25):9402-8. doi: 10.1523/JNEUROSCI.4800-14.2015.
PubMed PMID: 26109663.

• Dijkstra AA, Ingrassia A, de Menezes RX, van Kesteren RE, Rozemuller AJ,
Heutink P, van de Berg WD. Evidence for Immune Response, Axonal Dysfunction and Reduced Endocytosis in the Substantia Nigra in Early Stage Parkinson’s Disease. PLoS One 2015 Jun 18;10(6):e0128651. doi: 10.1371/journal.pone.0128651.
PubMed PMID: 26087293; PubMed Central PMCID: PMC4472235.

• Aarts E, Maroteaux G, Loos M, Koopmans B, Kovačević J, Smit AB, Verhage M,
Sluis Sv; Neuro-BSIK Mouse Phenomics Consortium.. The light spot test: Measuring anxiety in mice in an automated home-cage environment. Behav Brain Res. 2015 Nov 1;294:123-30. doi: 10.1016/j.bbr.2015.06.011.
PubMed PMID: 26072393.

• Giniatullina A, Maroteaux G, Geerts CJ, Koopmans B, Loos M, Klaassen R, Chen
N, van der Schors RC, van Nierop P, Li KW, de Jong J, Altrock WD, Cornelisse LN,
Toonen RF, van der Sluis S, Sullivan PF, Stiedl O, Posthuma D, Smit AB, Groffen
AJ, Verhage M. Functional characterization of the PCLO p.Ser4814Ala variant
associated with major depressive disorder reveals cellular but not behavioral
differences. Neuroscience 2015 Aug 6;300:518-38. doi:
10.1016/j.neuroscience.2015.05.047.
PubMed PMID: 26045179.

• Ferreira JS, Schmidt J, Rio P, Águas R, Rooyakkers A, Li KW, Smit AB, Craig
AM, Carvalho AL. GluN2B-Containing NMDA Receptors Regulate AMPA Receptor Traffic through Anchoring of the Synaptic Proteasome. J Neurosci. 2015 Jun
3;35(22):8462-79. doi: 10.1523/JNEUROSCI.3567-14.2015.
PubMed PMID: 26041915.

• Wiemhoefer A, Stargardt A, van der Linden WA, Renner MC, van Kesteren RE,
Stap J, Raspe MA, Tomkinson B, Kessels HW, Ovaa H, Overkleeft HS, Florea B, Reits EA. Tripeptidyl Peptidase II Mediates Levels of Nuclear Phosphorylated ERK1 and ERK2. Mol Cell Proteomics 2015 Aug;14(8):2177-93. doi: 10.1074/mcp.M114.043331.
PubMed PMID: 26041847; PubMed Central PMCID: PMC4528246.

• Chavarria-Siles I, White T, de Leeuw C, Goudriaan A, Lips E, Ehrlich S,
Turner JA, Calhoun VD, Gollub RL, Magnotta VA, Ho BC, Smit AB, Verheijen MH,
Posthuma D. Myelination-related genes are associated with decreased white matter integrity in schizophrenia. Eur J Hum Genet. 2016 Mar;24(3):381-6. doi:
10.1038/ejhg.2015.120. PubMed PMID: 26014434;
PubMed Central PMCID: PMC4757770.

• van der Kallen LR, Eggers R, Ehlert EM, Verhaagen J, Smit AB, van Kesteren
RE. Genetic Deletion of the Transcriptional Repressor NFIL3 Enhances Axon Growth In Vitro but Not Axonal Repair In Vivo. PLoS One 2015 May 20;10(5):e0127163. doi: 10.1371/journal.pone.0127163. PubMed PMID: 25993115;
PubMed Central PMCID: PMC4438979.

• Farzana F, Zalm R, Chen N, Li KW, Grant SG, Smit AB, Toonen RF, Verhage M.
Neurobeachin Regulates Glutamate- and GABA-Receptor Targeting to Synapses via Distinct Pathways. Mol Neurobiol. 2016 May;53(4):2112-23. doi:
10.1007/s12035-015-9164-8. PubMed PMID: 25934101;
PubMed Central PMCID:PMC4823379.

• Omrani A, van der Vaart T, Mientjes E, van Woerden GM, Hojjati MR, Li KW,
Gutmann DH, Levelt CN, Smit AB, Silva AJ, Kushner SA, Elgersma Y. HCN channels
are a novel therapeutic target for cognitive dysfunction in Neurofibromatosis
type 1. Mol Psychiatry 2015 Nov;20(11):1311-21. doi: 10.1038/mp.2015.48.
PubMed PMID: 25917366.

• Lenselink AM, Rotaru DC, Li KW, van Nierop P, Rao-Ruiz P, Loos M, van der
Schors R, Gouwenberg Y, Wortel J, Mansvelder HD, Smit AB, Spijker S. Strain
Differences in Presynaptic Function: PROTEOMICS, ULTRASTRUCTURE, AND PHYSIOLOGY OF HIPPOCAMPAL SYNAPSES IN DBA/2J AND C57Bl/6J MICE. * J Biol Chem.* 2015 Jun 19;290(25):15635-45. doi: 10.1074/jbc.M114.628776. PubMed PMID: 25911096;
PubMed Central PMCID: PMC4505475.

• Hilderink J, Spijker S, Carlotti F, Lange L, Engelse M, van Blitterswijk C,
de Koning E, Karperien M, van Apeldoorn A. Controlled aggregation of primary
human pancreatic islet cells leads to glucose-responsive pseudoislets comparable to native islets.* J Cell Mol Med.* 2015 Aug;19(8):1836-46. doi:
10.1111/jcmm.12555. PubMed PMID: 25782016;
PubMed Central PMCID: PMC4549034.

• de Leeuw C, Goudriaan A, Smit AB, Yu D, Mathews CA, Scharf JM; Tourette
Syndrome Association International Consortium for Genetics., Verheijen MH,
Posthuma D. Involvement of astrocyte metabolic coupling in Tourette syndrome
pathogenesis. Eur J Hum Genet. 2015 Nov;23(11):1519-22. doi:
10.1038/ejhg.2015.22.
PubMed PMID: 25735483; PubMed Central PMCID: PMC4613465.

• Dilekoz E, Houben T, Eikermann-Haerter K, Balkaya M, Lenselink AM, Whalen MJ, Spijker S, Ferrari MD, van den Maagdenberg AM, Ayata C. Migraine mutations impair hippocampal learning despite enhanced long-term potentiation. J Neurosci. 2015 Feb 25;35(8):3397-402. doi: 10.1523/JNEUROSCI.2630-14.2015.
PubMed PMID: 25716839; PubMed Central PMCID: PMC4339352.

• Rao-Ruiz P, Carney KE, Pandya N, van der Loo RJ, Verheijen MH, van Nierop P,
Smit AB, Spijker S. Time-dependent changes in the mouse hippocampal synaptic
membrane proteome after contextual fear conditioning. Hippocampus 2015
Nov;25(11):1250-61. doi: 10.1002/hipo.22432.
PubMed PMID: 25708624.

• Chen N, Koopmans F, Gordon A, Paliukhovich I, Klaassen RV, van der Schors RC, Peles E, Verhage M, Smit AB, Li KW. Interaction proteomics of canonical Caspr2 (CNTNAP2) reveals the presence of two Caspr2 isoforms with overlapping
interactomes. Biochim Biophys Acta. 2015 Jul;1854(7):827-33. doi:
10.1016/j.bbapap.2015.02.008.
PubMed PMID: 25707359.

• Remmelink E, Loos M, Koopmans B, Aarts E, van der Sluis S, Smit AB, Verhage
M; Neuro-BSIK Mouse Phenomics Consortium.. A 1-night operant learning task
without food-restriction differentiates among mouse strains in an automated
home-cage environment. Behav Brain Res. 2015 Apr 15;283:53-60. doi:
10.1016/j.bbr.2015.01.020.
PubMed PMID: 25601577.