Research
We investigate molecular and cellular mechanisms that underlie plasticity of synapses and neuronal circuitry in animal models, as well as the human brain.
Projects and Networks
MCN teams contribute to national and international research projects and consortiums
About us
The MCN department was initiated in 2003 and in its current form has ~40 lab members. MCN participates in Amsterdam Neuroscience. Photo: lab outing to France 2023
Our latest activities
Remote memory strength is shaped by retraction of astrocytes from cortical synapses
Recent work by the teams of Mark Verheijen and Michel van den Oever, published in Cell Reports, introduces a novel tool called Astro-GRASP to fluorescently label interaction between astrocyte processes and synapses on specific neuronal populations.
The intensity of a threatening experience shapes synaptic changes on cortical engram cells
A new study by the Memory Circuits and Molecular Engram teams, published in Nature Communications, reveals that memory-encoding cortical neurons functionally contribute to remote memory retrieval after a mild, but not strong, aversive event.
Janina Kupke receives NWO Veni grant
Dr. Janina Kupke has been awarded an NWO Veni grant for her project 'Bridging the epigenome and the synapse: resolving how memories persist'
