Ardesch DJ, Libedinsky I, Scholtens LH, Wei Y, van den Heuvel MP. Convergence of Brain Transcriptomic and Neuroimaging Patterns in Schizophrenia, Bipolar Disorder, Autism Spectrum Disorder, and Major Depressive Disorder. Biol Psychiatry Cogn Neurosci Neuroimaging. 2023 Jun;8(6):630-639. doi: 10.1016/j.bpsc.2022.12.013. Epub 2023 Jan 3. PMID: 37286292.

Batenburg KL, Rohde SK, Cornelissen-Steijger P, Breeuwsma N, Heine VM, Scheper W. A Human Neuron/Astrocyte Co-culture to Model Seeded and Spontaneous Intraneuronal Tau Aggregation. Curr Protoc. 2023 Oct;3(10):e900. doi: 10.1002/cpz1.900. PMID: 37801344.

Batenburg, K. L., Sestito, C., Cornelissen-Steijger, P., van Weering, J. R. T., Price, L. S., Heine, V. M., & Scheper, W. (2023). A 3D human co-culture to model neuron-astrocyte interactions in tauopathies. Biological procedures online, 25(1), 4. https://doi.org/10.1186/s12575-023-00194-2

Batenburg, K. L., Kasri, N. N., Heine, V. M., & Scheper, W. (2023). Intraneuronal tau aggregation induces the integrated stress response in astrocytes. Journal of molecular cell biology, 14(10), mjac071. https://doi.org/10.1093/jmcb/mjac071

Bazinet V, Hansen JY, Vos de Wael R, Bernhardt BC, van den Heuvel MP, Misic B. Assortative mixing in micro-architecturally annotated brain connectomes. Nat Commun. 2023 May 18;14(1):2850. doi: 10.1038/s41467-023-38585-4. PMID: 37202416; PMCID: PMC10195875.

Bresser T, Leerssen J, Hölsken S, Groote I, Foster-Dingley JC, van den Heuvel MP, Van Someren EJW. The role of brain white matter in depression resilience and response to sleep interventions. Brain Commun. 2023 Aug 2;5(4):fcad210. doi: 10.1093/braincomms/fcad210. PMID: 37554956; PMCID: PMC10406158.

de Hemptinne MC, Posthuma D. Addressing the ethical and societal challenges posed by genome-wide association studies of behavioral and brain-related traits. Nat Neurosci. 2023 Jun;26(6):932-941. doi: 10.1038/s41593-023-01333-4. Epub 2023 May 22. PMID: 37217727.

de Lange SC, Helwegen K, van den Heuvel MP. Structural and functional connectivity reconstruction with CATO – A Connectivity Analysis TOolbox. Neuroimage. 2023 Jun;273:120108. doi: 10.1016/j.neuroimage.2023.120108. Epub 2023 Apr 12. PMID: 37059156.

de Leeuw C, Werme J, Savage JE, Peyrot WJ, Posthuma D. On the interpretation of transcriptome-wide association studies. PLoS Genet. 2023 Sep 7;19(9):e1010921. doi: 10.1371/journal.pgen.1010921. PMID: 37676898; PMCID: PMC10508613.

de Sousa, A. A., Beaudet, A., Calvey, T., Bardo, A., Benoit, J., Charvet, C. J., Dehay, C., Gómez-Robles, A., Gunz, P., Heuer, K., van den Heuvel, M. P., Hurst, S., Lauters, P., Reed, D., Salagnon, M., Sherwood, C. C., Ströckens, F., Tawane, M., Todorov, O. S., Toro, R., … Wei, Y. (2023). From fossils to mind. Communications biology, 6(1), 636. https://doi.org/10.1038/s42003-023-04803-4

Dooves S, Kok LML, Holmes DB, Breeuwsma N, Breur M, Bugiani M, Wolf NI, Heine VM. Cortical interneuron development is affected in 4H leukodystrophy. Brain. 2023 Jul 3;146(7):2846-2860. doi: 10.1093/brain/awad017. PMID: 36729681; PMCID: PMC10316783.

Faskowitz J, Puxeddu MG, van den Heuvel MP, Mišić B, Yovel Y, Assaf Y, Betzel RF, Sporns O. Connectome topology of mammalian brains and its relationship to taxonomy and phylogeny. Front Neurosci. 2023 Jan 11;16:1044372. doi: 10.3389/fnins.2022.1044372. PMID: 36711139; PMCID: PMC9874302.

Fominykh V, Shadrin AA, Jaholkowski PP, Bahrami S, Athanasiu L, Wightman DP, Uffelmann E, Posthuma D, Selbæk G, Dale AM, Djurovic S, Frei O, Andreassen OA. Shared genetic loci between Alzheimer’s disease and multiple sclerosis: Crossroads between neurodegeneration and immune system. Neurobiol Dis. 2023 Jul;183:106174. doi: 10.1016/j.nbd.2023.106174. Epub 2023 Jun 5. PMID: 37286172.

Gruber M, Mauritz M, Meinert S, Grotegerd D, de Lange SC, Grumbach P, Goltermann J, Winter NR, Waltemate L, Lemke H, Thiel K, Winter A, Breuer F, Borgers T, Enneking V, Klug M, Brosch K, Meller T, Pfarr JK, Ringwald KG, Stein F, Opel N, Redlich R, Hahn T, Leehr EJ, Bauer J, Nenadić I, Kircher T, van den Heuvel MP, Dannlowski U, Repple J. Cognitive performance and brain structural connectome alterations in major depressive disorder. Psychol Med. 2023 Feb 8:1-12. doi: 10.1017/S0033291722004007. Epub ahead of print. PMID: 36752136.

Habets, P. C., Thomas, R. M., Milaneschi, Y., Jansen, R., Pool, R., Peyrot, W. J., Penninx, B. W. J. H., Meijer, O. C., van Wingen, G. A., & Vinkers, C. H. (2023). Multimodal Data Integration Advances Longitudinal Prediction of the Naturalistic Course of Depression and Reveals a Multimodal Signature of Remission During 2-Year Follow-up. Biological psychiatry, 94(12), 948–958. https://doi.org/10.1016/j.biopsych.2023.05.024

Hahn T, Winter NR, Ernsting J, Gruber M, Mauritz MJ, Fisch L, Leenings R, Sarink K, Blanke J, Holstein V, Emden D, Beisemann M, Opel N, Grotegerd D, Meinert S, Heindel W, Witt S, Rietschel M, Nöthen MM, Forstner AJ, Kircher T, Nenadic I, Jansen A, Müller-Myhsok B, Andlauer TFM, Walter M, van den Heuvel MP, Jamalabadi H, Dannlowski U, Repple J. Genetic, individual, and familial risk correlates of brain network controllability in major depressive disorder. Mol Psychiatry. 2023 Mar;28(3):1057-1063. doi: 10.1038/s41380-022-01936-6. Epub 2023 Jan 13. PMID: 36639510; PMCID: PMC10005934.

Hagenbeek, F. A., Hirzinger, J. S., Breunig, S., Bruins, S., Kuznetsov, D. V., Schut, K., Odintsova, V. V., & Boomsma, D. I. (2023). Maximizing the value of twin studies in health and behaviour. Nature human behaviour, 7(6), 849–860. https://doi.org/10.1038/s41562-023-01609-6

Helwegen K, Libedinsky I, van den Heuvel MP. Statistical power in network neuroscience. Trends Cogn Sci. 2023 Mar;27(3):282-301. doi: 10.1016/j.tics.2022.12.011. Epub 2023 Jan 30. PMID: 36725422.

Kaboodvand N, Iravani B, van den Heuvel MP, Persson J, Boden R. Macroscopic resting state model predicts theta burst stimulation response: A randomized trial. PLoS Comput Biol. 2023 Mar 6;19(3):e1010958. doi: 10.1371/journal.pcbi.1010958. PMID: 36877733; PMCID: PMC10019702.

Kipkemoi P, Kim HA, Christ B, O’Heir E, Allen J, Austin-Tse C, Baxter S, Brand H, Bryant S, Buser N, de Menil V, Eastman E, Murugasen S, Galvin A, Kombe M, Ngombo A, Mkubwa B, Mwangi P, Kipkoech C, Lovgren A, MacArthur DG, Melly B, Mwangasha K, Martin A, Nkambule LL, Sanchis-Juan A, Singer-Berk M, Talkowski ME, VanNoy G, van der Merwe C; NeuroDev Project; Newton C, O’Donnell-Luria A, Abubakar A, Donald KA, Robinson EB. Phenotype and genetic analysis of data collected within the first year of NeuroDev. Neuron. 2023 Sep 20;111(18):2800-2810.e5. doi: 10.1016/j.neuron.2023.06.010. Epub 2023 Jul 17. PMID: 37463579.

Lin BD, Pinzón-Espinosa J, Blouzard E, van der Horst MZ, Okhuijsen-Pfeifer C, van Eijk KR, Guloksuz S, Peyrot WJ, Luykx JJ; Genetic Risk and Outcome of Psychosis (GROUP) and Clozapine International Consortium (CLOZIN) Investigators. Associations Between Polygenic Risk Score Loading, Psychosis Liability, and Clozapine Use Among Individuals With Schizophrenia. JAMA Psychiatry. 2023 Feb 1;80(2):181-185. doi: 10.1001/jamapsychiatry.2022.4234. PMID: 36542388; PMCID: PMC9857760.

Malawsky DS, van Walree E, Jacobs BM, Heng TH, Huang QQ, Sabir AH, Rahman S, Sharif SM, Khan A, Mirkov MU; 23andMe Research Team; Genes & Health Research Team; Kuwahara H, Gao X, Alkuraya FS, Posthuma D, Newman WG, Griffiths CJ, Mathur R, van Heel DA, Finer S, O’Connell J, Martin HC. Influence of autozygosity on common disease risk across the phenotypic spectrum. Cell. 2023 Oct 12;186(21):4514-4527.e14. doi: 10.1016/j.cell.2023.08.028. Epub 2023 Sep 26. PMID: 37757828; PMCID: PMC10580289.

Pham, C., Andrzejczyk, K., Jurgens, S. J., Lekanne Deprez, R., Palm, K. C. A., Vermeer, A. M. C., Nijman, J., Christiaans, I., Barge-Schaapveld, D. Q. C. M., van Dessel, P. F. H. M., Beekman, L., Choi, S. H., Lubitz, S. A., Skoric-Milosavljevic, D., van den Bersselaar, L., Jansen, P. R., Copier, J. S., Ellinor, P. T., Wilde, A. A. M., Bezzina, C. R., … Lodder, E. M. (2023). Genetic Burden of TNNI3K in Diagnostic Testing of Patients With Dilated Cardiomyopathy and Supraventricular Arrhythmias. Circulation. Genomic and precision medicine,16(4), 328–336. https://doi.org/10.1161/CIRCGEN.122.003975

Repple, J., Gruber, M., Mauritz, M., de Lange, S. C., Winter, N. R., Opel, N., Goltermann, J., Meinert, S., Grotegerd, D., Leehr, E. J., Enneking, V., Borgers, T., Klug, M., Lemke, H., Waltemate, L., Thiel, K., Winter, A., Breuer, F., Grumbach, P., Hofmann, H., … Dannlowski, U. (2023). Shared and Specific Patterns of Structural Brain Connectivity Across Affective and Psychotic Disorders. Biological psychiatry, 93(2), 178–186. https://doi.org/10.1016/j.biopsych.2022.05.031

Roelfs D, Frei O, van der Meer D, Tissink E, Shadrin A, Alnaes D, Andreassen OA, Westlye LT, Kaufmann T. Shared genetic architecture between mental health and the brain functional connectome in the UK Biobank. BMC Psychiatry. 2023 Jun 23;23(1):461. doi: 10.1186/s12888-023-04905-7. PMID: 37353766; PMCID: PMC10290393.

Savage JE; Spit for Science Working Group; Dick DM. Internalizing and externalizing subtypes of alcohol misuse and their relation to drinking motives. Addict Behav. 2023 Jan;136:107461. doi: 10.1016/j.addbeh.2022.107461. Epub 2022 Aug 27. PMID: 36063573.

Savage JE; Spit for Science Working Group; Dick DM. Drinking Motives, Alcohol Misuse, and Internalizing and Externalizing Psychopathology across College: A Cross-Lagged Panel Study. Subst Use Misuse. 2023;58(11):1377-1387. doi: 10.1080/10826084.2023.2223269. Epub 2023 Jun 20. PMID: 37339914.

Scheepbouwer C, Aparicio-Puerta E, Gomez-Martin C, Verschueren H, van Eijndhoven M, Wedekind LE, Giannoukakos S, Hijmering N, Gasparotto L, van der Galien HT, van Rijn RS, Aronica E, Kibbelaar R, Heine VM, Wesseling P, Noske DP, Vandertop WP, de Jong D, Pegtel DM, Hackenberg M, Wurdinger T, Gerber A, Koppers-Lalic D. ALL-tRNAseq enables robust tRNA profiling in tissue samples. Genes Dev. 2023 Mar 1;37(5-6):243-257. doi: 10.1101/gad.350233.122. Epub 2023 Feb 21. PMID: 36810209; PMCID: PMC10111867.

de Sousa AA, Beaudet A, Calvey T, Bardo A, Benoit J, Charvet CJ, Dehay C, Gómez-Robles A, Gunz P, Heuer K, van den Heuvel MP, Hurst S, Lauters P, Reed D, Salagnon M, Sherwood CC, Ströckens F, Tawane M, Todorov OS, Toro R, Wei Y. From fossils to mind. Commun Biol. 2023 Jun 13;6(1):636. doi: 10.1038/s42003-023-04803-4. PMID: 37311857; PMCID: PMC10262152.

Stein F, Gruber M, Mauritz M, Brosch K, Pfarr JK, Ringwald KG, Thomas-Odenthal F, Wroblewski A, Evermann U, Steinsträter O, Grumbach P, Thiel K, Winter A, Bonnekoh LM, Flinkenflügel K, Goltermann J, Meinert S, Grotegerd D, Bauer J, Opel N, Hahn T, Leehr EJ, Jansen A, de Lange SC, van den Heuvel M, Nenadić I, Krug A, Dannlowski U, Repple J, Kircher T. Brain structural network connectivity of formal thought disorder dimensions in affective and psychotic disorders. Biol Psychiatry. 2023 May 17:S0006-3223(23)01297-0. doi: 10.1016/j.biopsych.2023.05.010. Epub ahead of print. PMID: 37207935.

Thijssen, A. B., Spit for Science Working Group, Dick, D. M., Posthuma, D., & Savage, J. E. (2023). Investigating genetically stratified subgroups to better understand the etiology of alcohol misuse. Molecular psychiatry, 28(10), 4225–4233. https://doi.org/10.1038/s41380-023-02174-0

Tielbeek, J. J., van der Hooft, M., Cohn, M. D., van de Ven, P. M., Polderman, T. J., Veltman, D. J., Posthuma, D., Schuengel, C., van Domburgh, L., & Popma, A. (2023). The association between delinquent peer affiliation and disruptive behavior interacts with functional brain correlates of reward sensitivity: a biosocial interaction study in adolescent delinquents. Psychological medicine, 1–8. Advance online publication. https://doi.org/10.1017/S0033291723003380

Uffelmann E, Posthuma D, Peyrot WJ. Genome-wide association studies of polygenic risk score-derived phenotypes may lead to inflated false positive rates. Sci Rep. 2023 Mar 14;13(1):4219. doi: 10.1038/s41598-023-29428-9. PMID: 36918594; PMCID: PMC10015046.

van Berkel, A. A., Lammertse, H. C. A., Öttl, M., Koopmans, F., Misra-Isrie, M., Meijer, M., Dilena, R., van Hasselt, P. M., Engelen, M., van Haelst, M., Smit, A. B., van der Sluis, S., Toonen, R. F., & Verhage, M. (2023). Reduced MUNC18-1 Levels, Synaptic Proteome Changes, and Altered Network Activity in STXBP1-Related Disorder Patient Neurons. Biological psychiatry global open science, 4(1), 284–298. https://doi.org/10.1016/j.bpsgos.2023.05.004

van den Heuvel MP, Ardesch DJ, Scholtens LH, de Lange SC, van Haren NEM, Sommer IEC, Dannlowski U, Repple J, Preuss TM, Hopkins WD, Rilling JK. Human and chimpanzee shared and divergent neurobiological systems for general and specific cognitive brain functions. Proc Natl Acad Sci U S A. 2023 May 30;120(22):e2218565120. doi: 10.1073/pnas.2218565120. Epub 2023 May 22. PMID: 37216540; PMCID: PMC10235977.

van Riel L, Jansen PR, Boerrigter BG, van Moorselaar RJA, van Haelst MM, Wolthuis RMF, van de Beek I, Houweling AC. Correspondence on “Frequency of truncating FLCN variants and Birt-Hogg-Dubé-associated phenotypes in a health care system population” by Savatt et al. Genet Med. 2023 Jan;25(1):158-160. doi: 10.1016/j.gim.2022.08.033. Epub 2022 Nov 16. PMID: 36383210.

Wightman DP, Savage JE, de Leeuw CA, Jansen IE, Posthuma D. Rare variant aggregation in 148,508 exomes identifies genes associated with proxy dementia. Sci Rep. 2023 Feb 7;13(1):2179. doi: 10.1038/s41598-023-29108-8. PMID: 36750708; PMCID: PMC9905079.

Wightman DP, Savage JE, Tissink E, Romero C, Jansen IE, Posthuma D. The genetic overlap between Alzheimer’s disease, amyotrophic lateral sclerosis, Lewy body dementia, and Parkinson’s disease. Neurobiol Aging. 2023 Jul;127:99-112. doi: 10.1016/j.neurobiolaging.2023.03.004. Epub 2023 Mar 12. PMID: 37045620.

Winter, A., Gruber, M., Thiel, K., Flinkenflügel, K., Meinert, S., Goltermann, J., Winter, N. R., Borgers, T., Stein, F., Jansen, A., Brosch, K., Wroblewski, A., Thomas-Odenthal, F., Usemann, P., Straube, B., Alexander, N., Jamalabadi, H., Nenadić, I., Bonnekoh, L. M., Dohm, K., … Dannlowski, U. (2023). Shared and distinct structural brain networks related to childhood maltreatment and social support: connectome-based predictive modeling. Molecular psychiatry, 10.1038/s41380-023-02252-3. Advance online publication. https://doi.org/10.1038/s41380-023-02252-3

Woodfield J, Chin RFM, van Schooneveld MMJ, van den Heuvel M, Bastin ME, Braun KPJ. The association of structural connectome efficiency with cognition in children with epilepsy. Epilepsy Behav. 2023 Oct 14;148:109462. doi: 10.1016/j.yebeh.2023.109462. Epub ahead of print. PMID: 37844437.

Consortium papers

Le Guen, Y., Luo, G., Ambati, A., Damotte, V., Jansen, I., Yu, E., Nicolas, A., de Rojas, I., Peixoto Leal, T., Miyashita, A., Bellenguez, C., Lian, M. M., Parveen, K., Morizono, T., Park, H., Grenier-Boley, B., Naito, T., Küçükali, F., Talyansky, S. D., Yogeshwar, S. M., … Mignot, E. (2023). Multiancestry analysis of the HLA locus in Alzheimer’s and Parkinson’s diseases uncovers a shared adaptive immune response mediated by HLA-DRB1*04 subtypes. Proceedings of the National Academy of Sciences of the United States of America, 120(36), e2302720120. https://doi.org/10.1073/pnas.2302720120