2020
Alsaqati M, Heine VM, Harwood AJ. Pharmacological intervention to restore connectivity deficits of neuronal networks derived from ASD patient iPSC with a TSC2 mutation. Mol Autism. 2020 Oct 19;11(1):80. doi: 10.1186/s13229-020-00391-w. PMID: 33076974; PMCID: PMC7574213.
Coleman JRI, Peyrot WJ, Purves KL, Davis KAS, Rayner C, Choi SW, Hübel C, Gaspar HA, Kan C, Van der Auwera S, Adams MJ, Lyall DM, Choi KW; on the behalf of Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Dunn EC, Vassos E, Danese A, Maughan B, Grabe HJ, Lewis CM, O’Reilly PF, McIntosh AM, Smith DJ, Wray NR, Hotopf M, Eley TC, Breen G. Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank. Mol Psychiatry. 2020 Jul;25(7):1430-1446. doi: 10.1038/s41380-019-0546-6. Epub 2020 Jan 23. Erratum in: Mol Psychiatry. 2020 May 18;: PMID: 31969693; PMCID: PMC7305950.
Drakulic D, Djurovic S, Syed YA, Trattaro S, Caporale N, Falk A, Ofir R, Heine VM, Chawner SJRA, Rodriguez-Moreno A, van den Bree MBM, Testa G, Petrakis S, Harwood AJ. Copy number variants (CNVs): a powerful tool for iPSC-based modelling of ASD. Mol Autism. 2020 Jun 1;11(1):42. doi: 10.1186/s13229-020-00343-4. PMID: 32487215; PMCID: PMC7268297.
Depla JA, Sogorb-Gonzalez M, Mulder LA, Heine VM, Konstantinova P, van Deventer SJ, Wolthers KC, Pajkrt D, Sridhar A, Evers MM. Cerebral Organoids: A Human Model for AAV Capsid Selection and Therapeutic Transgene Efficacy in the Brain. Mol Ther Methods Clin Dev. 2020 Jun 1;18:167-175. doi: 10.1016/j.omtm.2020.05.028. PMID: 32637448; PMCID: PMC7327852.
Hillen AEJ, Heine VM. Glutamate Carrier Involvement in Mitochondrial Dysfunctioning in the Brain White Matter. Front Mol Biosci. 2020 Jul 21;7:151. doi: 10.3389/fmolb.2020.00151. PMID: 32793632; PMCID: PMC7385250.
Jansen AG, Dieleman GC, Jansen PR, Verhulst FC, Posthuma D, Polderman TJC. Psychiatric Polygenic Risk Scores as Predictor for Attention Deficit/Hyperactivity Disorder and Autism Spectrum Disorder in a Clinical Child and Adolescent Sample. Behav Genet. 2020 Jul;50(4):203-212. doi: 10.1007/s10519-019-09965-8. Epub 2019 Jul 25. PMID: 31346826.
Jansen PR, Nagel M, Watanabe K, Wei Y, Savage JE, de Leeuw CA, van den Heuvel MP, van der Sluis S, Posthuma D. Genome-wide meta-analysis of brain volume identifies genomic loci and genes shared with intelligence. Nat Commun. 2020 Nov 5;11(1):5606. doi: 10.1038/s41467-020-19378-5. PMID: 33154357; PMCID: PMC7644755.
Meier JM, van der Burgh HK, Nitert AD, Bede P, de Lange SC, Hardiman O, van den Berg LH, van den Heuvel MP.Connectome-Based Propagation Model in Amyotrophic Lateral Sclerosis. Ann Neurol. 2020 May;87(5):725-738. doi: 10.1002/ana.25706. Epub 2020 Mar 11. PMID: 32072667
Nagel M, Speed D, van der Sluis S, Østergaard SD. Genome-wide association study of the sensitivity to environmental stress and adversity neuroticism cluster. Acta Psychiatr Scand. 2020 May;141(5):476-478. doi:10.1111/acps.13155. PMID: 31972866.
Repple J, Mauritz M, Meinert S, de Lange SC, Grotegerd D, Opel N, Redlich R, Hahn T, Förster K, Leehr EJ, Winter N, Goltermann J, Enneking V, Fingas SM, Lemke H, Waltemate L, Nenadic I, Krug A, Brosch K, Schmitt S, Stein F, Meller T, Jansen A, Steinsträter O, Baune BT, Kircher T, Dannlowski U, van den Heuvel MP. Severity of current depression and remission status are associated with structural connectome alterations in major depressive disorder. Mol Psychiatry. 2020 Jul;25(7):1550-1558. doi: 10.1038/s41380-019-0603-1. Epub 2019 Nov 22. PMID: 31758093
Reus LM, Stringer S, Posthuma D, Teunissen CE, Scheltens P, Pijnenburg YAL, Visser PJ, Tijms BM; Alzheimer’s Disease Neuroimaging Initiative. Degree of genetic liability for Alzheimer’s disease associated with specific proteomic profiles in cerebrospinal fluid. Neurobiol Aging. 2020 Sep;93:144.e1-144.e15. doi: 10.1016/j.neurobiolaging.2020.03.012. Epub 2020 Mar 24. PMID: 32307133.
Sabrin KM, Wei Y, van den Heuvel MP, Dovrolis C. The hourglass organization of the Caenorhabditis elegans connectome. PLoS Comput Biol. 2020 Feb 6;16(2):e1007526. doi: 10.1371/journal.pcbi.1007526. eCollection 2020 Feb.
PMID: 32027645
Smeland OB, Bahrami S, Frei O, Shadrin A, O’Connell K, Savage J, Watanabe K, Krull F, Bettella F, Steen NE, Ueland T, Posthuma D, Djurovic S, Dale AM, Andreassen OA. Genome-wide analysis reveals extensive genetic overlap between schizophrenia, bipolar disorder, and intelligence. Mol Psychiatry. 2020 Apr;25(4):844-853. doi: 10.1038/s41380-018-0332-x. PMID: 30610197
Tielbeek JJ, Boutwell BB. Exploring the Genomic Architectures of Health, Physical Traits and Antisocial Behavioral Outcomes: A Brief Report. Front Psychiatry. 2020 Jun 25;11:539. doi: 10.3389/fpsyt.2020.00539. PMID: 32670102; PMCID: PMC7330713.
van der Burgh HK, Westeneng HJ, Walhout R, van Veenhuijzen K, Tan HHG, Meier JM, Bakker LA, Hendrikse J, van Es MA, Veldink JH, van den Heuvel MP, van den Berg LH. Multimodal longitudinal study of structural brain involvement in amyotrophic lateral sclerosis. Neurology. 2020 Jun 16;94(24):e2592-e2604. doi:10.1212/WNL.0000000000009498. Epub 2020 May 15. PMID: 32414878; PMCID: PMC7455328.
van Walree ES, Dombrowsky G, Jansen IE, Mirkov MU, Zwart R, Ilgun A, Guo D, Clur SB, Amin AS, Savage JE, van der Wal AC, Waisfisz Q, Maugeri A, Wilsdon A, Bu’Lock FA, Hurles ME, Dittrich S, Berger F, Audain Martinez E, Christoffels VM, Hitz MP, Milewicz DM, Posthuma D, Meijers-Heijboer H, Postma AV, Mathijssen IB. Germline variants in HEY2 functional domains lead to congenital heart defects and thoracic aortic aneurysms. Genet Med. 2021 Jan;23(1):103-110. doi: 10.1038/s41436-020-00939-4. Epub 2020 Aug 21. PMID: 32820247.
Varderidou-Minasian S, Hinz L, Hagemans D, Posthuma D, Altelaar M, Heine VM. Quantitative proteomic analysis of Rett iPSC-derived neuronal progenitors. Mol Autism. 2020 May 27;11(1):38. doi: 10.1186/s13229-020-00344-3. PMID: 32460858; PMCID: PMC7251722.
Warren EC, Dooves S, Lugarà E, Damstra-Oddy J, Schaf J, Heine VM, Walker MC, Williams RSB. Decanoic acid inhibits mTORC1 activity independent of glucose and insulin signaling. Proc Natl Acad Sci U S A. 2020 Sep 22;117(38):23617-23625. doi: 10.1073/pnas.2008980117. Epub 2020 Sep 2. PMID: 32879008; PMCID: PMC7519326.
Zhang J, Scholtens LH, Wei Y, van den Heuvel MP, Chanes L, Barrett LF.Topography Impacts Topology: Anatomically Central Areas Exhibit a “High-Level Connector” Profile in the Human Cortex. Cereb Cortex. 2020 Mar 14;30(3):1357-1365. doi: 10.1093/cercor/bhz171. PMID: 31504277
Consortium papers
Bryois J, Skene NG, Hansen TF, Kogelman LJA, Watson HJ, Liu Z; Eating Disorders Working Group of the Psychiatric Genomics Consortium; International Headache Genetics Consortium; 23andMe Research Team, Brueggeman L, Breen G, Bulik CM, Arenas E, Hjerling-Leffler J, Sullivan PF. Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson’s disease. Nat Genet. 2020 May;52(5):482-493. doi: 10.1038/s41588-020-0610-9. Epub 2020 Apr 27. PMID: 32341526; PMCID: PMC7930801.
Coleman JRI, Gaspar HA, Bryois J; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Breen G. The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls. Biol Psychiatry. 2020 Jul 15;88(2):169-184. doi: 10.1016/j.biopsych.2019.10.015. Epub 2019 Nov 1. PMID: 31926635; PMCID: PMC8136147.
Erzurumluoglu AM, Liu M, Jackson VE, Barnes DR, Datta G, Melbourne CA, Young R, Batini C, Surendran P, Jiang T, Adnan SD, Afaq S, Agrawal A, Altmaier E, Antoniou AC, Asselbergs FW, Baumbach C, Bierut L, Bertelsen S, Boehnke M, Bots ML, Brazel DM, Chambers JC, Chang-Claude J, Chen C, Corley J, Chou YL, David SP, de Boer RA, de Leeuw CA, Dennis JG, Dominiczak AF, Dunning AM, Easton DF, Eaton C, Elliott P, Evangelou E, Faul JD, Foroud T, Goate A, Gong J, Grabe HJ, Haessler J, Haiman C, Hallmans G, Hammerschlag AR, Harris SE, Hattersley A, Heath A, Hsu C, Iacono WG, Kanoni S, Kapoor M, Kaprio J, Kardia SL, Karpe F, Kontto J, Kooner JS, Kooperberg C, Kuulasmaa K, Laakso M, Lai D, Langenberg C, Le N, Lettre G, Loukola A, Luan J, Madden PAF, Mangino M, Marioni RE, Marouli E, Marten J, Martin NG, McGue M, Michailidou K, Mihailov E, Moayyeri A, Moitry M, Müller-Nurasyid M, Naheed A, Nauck M, Neville MJ, Nielsen SF, North K, Perola M, Pharoah PDP, Pistis G, Polderman TJ, Posthuma D, Poulter N, Qaiser B, Rasheed A, Reiner A, Renström F, Rice J, Rohde R, Rolandsson O, Samani NJ, Samuel M, Schlessinger D, Scholte SH, Scott RA, Sever P, Shao Y, Shrine N, Smith JA, Starr JM, Stirrups K, Stram D, Stringham HM, Tachmazidou I, Tardif JC, Thompson DJ, Tindle HA, Tragante V, Trompet S, Turcot V, Tyrrell J, Vaartjes I, van der Leij AR, van der Meer P, Varga TV, Verweij N, Völzke H, Wareham NJ, Warren HR, Weir DR, Weiss S, Wetherill L, Yaghootkar H, Yavas E, Jiang Y, Chen F, Zhan X, Zhang W, Zhao W, Zhao W, Zhou K, Amouyel P, Blankenberg S, Caulfield MJ, Chowdhury R, Cucca F, Deary IJ, Deloukas P, Di Angelantonio E, Ferrario M, Ferrières J, Franks PW, Frayling TM, Frossard P, Hall IP, Hayward C, Jansson JH, Jukema JW, Kee F, Männistö S, Metspalu A, Munroe PB, Nordestgaard BG, Palmer CNA, Salomaa V, Sattar N, Spector T, Strachan DP; Understanding Society Scientific Group, EPIC-CVD, GSCAN, Consortium for Genetics of Smoking Behaviour, CHD Exome+ consortium, van der Harst P, Zeggini E, Saleheen D, Butterworth AS, Wain LV, Abecasis GR, Danesh J, Tobin MD, Vrieze S, Liu DJ, Howson JMM. Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci. Mol Psychiatry. 2020 Oct;25(10):2392-2409. doi: 10.1038/s41380-018-0313-0. Epub 2019 Jan 7. PMID: 30617275; PMCID: PMC7515840.
Glanville KP, Coleman JRI, Hanscombe KB, Euesden J, Choi SW, Purves KL, Breen G, Air TM, Andlauer TFM, Baune BT, Binder EB, Blackwood DHR, Boomsma DI, Buttenschøn HN, Colodro-Conde L, Dannlowski U, Direk N, Dunn EC, Forstner AJ, de Geus EJC, Grabe HJ, Hamilton SP, Jones I, Jones LA, Knowles JA, Kutalik Z, Levinson DF, Lewis G, Lind PA, Lucae S, Magnusson PK, McGuffin P, McIntosh AM, Milaneschi Y, Mors O, Mostafavi S, Müller-Myhsok B, Pedersen NL, Penninx BWJH, Potash JB, Preisig M, Ripke S, Shi J, Shyn SI, Smoller JW, Streit F, Sullivan PF, Tiemeier H, Uher R, Van der Auwera S, Weissman MM; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, O’Reilly PF, Lewis CM. Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression. Biol Psychiatry. 2020 Mar 1;87(5):419-430. doi: 10.1016/j.biopsych.2019.06.031. Epub 2019 Aug 5. PMID: 31570195; PMCID: PMC7001040.
Grasby KL, Jahanshad N, Painter JN, Colodro-Conde L, Bralten J, Hibar DP, Lind PA, Pizzagalli F, Ching CRK, McMahon MAB, Shatokhina N, Zsembik LCP, Thomopoulos SI, Zhu AH, Strike LT, Agartz I, Alhusaini S, Almeida MAA, Alnæs D, Amlien IK, Andersson M, Ard T, Armstrong NJ, Ashley-Koch A, Atkins JR, Bernard M, Brouwer RM, Buimer EEL, Bülow R, Bürger C, Cannon DM, Chakravarty M, Chen Q, Cheung JW, Couvy-Duchesne B, Dale AM, Dalvie S, de Araujo TK, de Zubicaray GI, de Zwarte SMC, den Braber A, Doan NT, Dohm K, Ehrlich S, Engelbrecht HR, Erk S, Fan CC, Fedko IO, Foley SF, Ford JM, Fukunaga M, Garrett ME, Ge T, Giddaluru S, Goldman AL, Green MJ, Groenewold NA, Grotegerd D, Gurholt TP, Gutman BA, Hansell NK, Harris MA, Harrison MB, Haswell CC, Hauser M, Herms S, Heslenfeld DJ, Ho NF, Hoehn D, Hoffmann P, Holleran L, Hoogman M, Hottenga JJ, Ikeda M, Janowitz D, Jansen IE, Jia T, Jockwitz C, Kanai R, Karama S, Kasperaviciute D, Kaufmann T, Kelly S, Kikuchi M, Klein M, Knapp M, Knodt AR, Krämer B, Lam M, Lancaster TM, Lee PH, Lett TA, Lewis LB, Lopes-Cendes I, Luciano M, Macciardi F, Marquand AF, Mathias SR, Melzer TR, Milaneschi Y, Mirza-Schreiber N, Moreira JCV, Mühleisen TW, Müller-Myhsok B, Najt P, Nakahara S, Nho K, Olde Loohuis LM, Orfanos DP, Pearson JF, Pitcher TL, Pütz B, Quidé Y, Ragothaman A, Rashid FM, Reay WR, Redlich R, Reinbold CS, Repple J, Richard G, Riedel BC, Risacher SL, Rocha CS, Mota NR, Salminen L, Saremi A, Saykin AJ, Schlag F, Schmaal L, Schofield PR, Secolin R, Shapland CY, Shen L, Shin J, Shumskaya E, Sønderby IE, Sprooten E, Tansey KE, Teumer A, Thalamuthu A, Tordesillas-Gutiérrez D, Turner JA, Uhlmann A, Vallerga CL, van der Meer D, van Donkelaar MMJ, van Eijk L, van Erp TGM, van Haren NEM, van Rooij D, van Tol MJ, Veldink JH, Verhoef E, Walton E, Wang M, Wang Y, Wardlaw JM, Wen W, Westlye LT, Whelan CD, Witt SH, Wittfeld K, Wolf C, Wolfers T, Wu JQ, Yasuda CL, Zaremba D, Zhang Z, Zwiers MP, Artiges E, Assareh AA, Ayesa-Arriola R, Belger A, Brandt CL, Brown GG, Cichon S, Curran JE, Davies GE, Degenhardt F, Dennis MF, Dietsche B, Djurovic S, Doherty CP, Espiritu R, Garijo D, Gil Y, Gowland PA, Green RC, Häusler AN, Heindel W, Ho BC, Hoffmann WU, Holsboer F, Homuth G, Hosten N, Jack CR Jr, Jang M, Jansen A, Kimbrel NA, Kolskår K, Koops S, Krug A, Lim KO, Luykx JJ, Mathalon DH, Mather KA, Mattay VS, Matthews S, Mayoral Van Son J, McEwen SC, Melle I, Morris DW, Mueller BA, Nauck M, Nordvik JE, Nöthen MM, O’Leary DS, Opel N, Martinot MP, Pike GB, Preda A, Quinlan EB, Rasser PE, Ratnakar V, Reppermund S, Steen VM, Tooney PA, Torres FR, Veltman DJ, Voyvodic JT, Whelan R, White T, Yamamori H, Adams HHH, Bis JC, Debette S, Decarli C, Fornage M, Gudnason V, Hofer E, Ikram MA, Launer L, Longstreth WT, Lopez OL, Mazoyer B, Mosley TH, Roshchupkin GV, Satizabal CL, Schmidt R, Seshadri S, Yang Q; Alzheimer’s Disease Neuroimaging Initiative; CHARGE Consortium; EPIGEN Consortium; IMAGEN Consortium; SYS Consortium; Parkinson’s Progression Markers Initiative, Alvim MKM, Ames D, Anderson TJ, Andreassen OA, Arias-Vasquez A, Bastin ME, Baune BT, Beckham JC, Blangero J, Boomsma DI, Brodaty H, Brunner HG, Buckner RL, Buitelaar JK, Bustillo JR, Cahn W, Cairns MJ, Calhoun V, Carr VJ, Caseras X, Caspers S, Cavalleri GL, Cendes F, Corvin A, Crespo-Facorro B, Dalrymple-Alford JC, Dannlowski U, de Geus EJC, Deary IJ, Delanty N, Depondt C, Desrivières S, Donohoe G, Espeseth T, Fernández G, Fisher SE, Flor H, Forstner AJ, Francks C, Franke B, Glahn DC, Gollub RL, Grabe HJ, Gruber O, Håberg AK, Hariri AR, Hartman CA, Hashimoto R, Heinz A, Henskens FA, Hillegers MHJ, Hoekstra PJ, Holmes AJ, Hong LE, Hopkins WD, Hulshoff Pol HE, Jernigan TL, Jönsson EG, Kahn RS, Kennedy MA, Kircher TTJ, Kochunov P, Kwok JBJ, Le Hellard S, Loughland CM, Martin NG, Martinot JL, McDonald C, McMahon KL, Meyer-Lindenberg A, Michie PT, Morey RA, Mowry B, Nyberg L, Oosterlaan J, Ophoff RA, Pantelis C, Paus T, Pausova Z, Penninx BWJH, Polderman TJC, Posthuma D, Rietschel M, Roffman JL, Rowland LM, Sachdev PS, Sämann PG, Schall U, Schumann G, Scott RJ, Sim K, Sisodiya SM, Smoller JW, Sommer IE, St Pourcain B, Stein DJ, Toga AW, Trollor JN, Van der Wee NJA, van ‘t Ent D, Völzke H, Walter H, Weber B, Weinberger DR, Wright MJ, Zhou J, Stein JL, Thompson PM, Medland SE; Enhancing NeuroImaging Genetics through Meta Analysis Consortium (ENIGMA)—Genetics working group. The genetic architecture of the human cerebral cortex. Science. 2020 Mar 20;367(6484):eaay6690. doi: 10.1126/science.aay6690. PMID: 32193296; PMCID: PMC7295264.
Hofer E, Roshchupkin GV, Adams HHH, Knol MJ, Lin H, Li S, Zare H, Ahmad S, Armstrong NJ, Satizabal CL, Bernard M, Bis JC, Gillespie NA, Luciano M, Mishra A, Scholz M, Teumer A, Xia R, Jian X, Mosley TH, Saba Y, Pirpamer L, Seiler S, Becker JT, Carmichael O, Rotter JI, Psaty BM, Lopez OL, Amin N, van der Lee SJ, Yang Q, Himali JJ, Maillard P, Beiser AS, DeCarli C, Karama S, Lewis L, Harris M, Bastin ME, Deary IJ, Veronica Witte A, Beyer F, Loeffler M, Mather KA, Schofield PR, Thalamuthu A, Kwok JB, Wright MJ, Ames D, Trollor J, Jiang J, Brodaty H, Wen W, Vernooij MW, Hofman A, Uitterlinden AG, Niessen WJ, Wittfeld K, Bülow R, Völker U, Pausova Z, Bruce Pike G, Maingault S, Crivello F, Tzourio C, Amouyel P, Mazoyer B, Neale MC, Franz CE, Lyons MJ, Panizzon MS, Andreassen OA, Dale AM, Logue M, Grasby KL, Jahanshad N, Painter JN, Colodro-Conde L, Bralten J, Hibar DP, Lind PA, Pizzagalli F, Stein JL, Thompson PM, Medland SE; ENIGMA consortium, Sachdev PS, Kremen WS, Wardlaw JM, Villringer A, van Duijn CM, Grabe HJ, Longstreth WT Jr, Fornage M, Paus T, Debette S, Ikram MA, Schmidt H, Schmidt R, Seshadri S. Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults. Nat Commun. 2020 Sep 22;11(1):4796. doi: 10.1038/s41467-020-18367-y. PMID: 32963231; PMCID: PMC7508833.
Kamitaki N, Sekar A, Handsaker RE, de Rivera H, Tooley K, Morris DL, Taylor KE, Whelan CW, Tombleson P, Loohuis LMO; Schizophrenia Working Group of the Psychiatric Genomics Consortium, Boehnke M, Kimberly RP, Kaufman KM, Harley JB, Langefeld CD, Seidman CE, Pato MT, Pato CN, Ophoff RA, Graham RR, Criswell LA, Vyse TJ, McCarroll SA. Complement genes contribute sex-biased vulnerability in diverse disorders. Nature. 2020 Jun;582(7813):577-581. doi: 10.1038/s41586 020-2277-x. Epub 2020 May 11. PMID: 32499649; PMCID: PMC7319891.
PRIMatE Data Exchange (PRIME-DE) Global Collaboration Workshop and Consortium. Electronic address: michael.milham@childmind.org; PRIMatE Data Exchange (PRIME-DE) Global Collaboration Workshop and Consortium. Accelerating the Evolution of Nonhuman Primate Neuroimaging. Neuron. 2020 Feb 19;105(4):600-603. doi: 10.1016/j.neuron.2019.12.023. PMID: 32078795; PMCID: PMC7610430.
Shen X, Howard DM, Adams MJ, Hill WD, Clarke TK; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Deary IJ, Whalley HC, McIntosh AM. A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank. Nat Commun. 2020 May 8;11(1):2301. doi: 10.1038/s41467-020-16022-0. PMID: 32385265; PMCID: PMC7210889.
Siewert KM, Klarin D, Damrauer SM, Chang KM, Tsao PS, Assimes TL, Davey Smith G, Voight BF; The International Headache Genetics Consortium. Cross-trait analyses with migraine reveal widespread pleiotropy and suggest a vascular component to migraine headache. Int J Epidemiol. 2020 Jun 1;49(3):1022-1031. doi: 10.1093/ije/dyaa050. Erratum in: Int J Epidemiol. 2020 Oct 1;49(5):1759. PMID: 32306029; PMCID: PMC7394956.